New Publication in Bioinformatics

New Publication in Bioinformatics

New publication about “Network-guided search for genetic heterogeneity between gene pairs” just got published in Bioinformatics: https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btaa581/5861532

We propose a novel method for finding pairs of interacting genes that are, upon combination, associated with a phenotype of interest under a model of genetic heterogeneity. We guide the interaction search using biological prior knowledge in the form of protein-protein interaction networks. Our method controls type I error and outperforms state-of-the-art methods with respect to statistical power. Additionally, we find novel associations for multiple A. thaliana phenotypes, and for a study of rare variants in migraine patients.

Two new research projects are funded!

We are pleased to announce that two new research projects will be funded by the Federal Office for Agriculture and Food as well as the Bayerisches Staatsministerium für Ernährung, Landwirtschaft und Forsten.

New Publication in Briefings in Bioinformatics

New Publication in Briefings in Bioinformatics

We are pleased to announce our new review paper describing challenges in amplicon and metagenomics sequencing, which has just been published in Briefings in Bioinformatics (https://doi.org/10.1093/bib/bbz155).