News

New Publication in Bioinformatics

New Publication in Bioinformatics

New publication about “Network-guided search for genetic heterogeneity between gene pairs” just got published in Bioinformatics: https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btaa581/5861532

We propose a novel method for finding pairs of interacting genes that are, upon combination, associated with a phenotype of interest under a model of genetic heterogeneity. We guide the interaction search using biological prior knowledge in the form of protein-protein interaction networks. Our method controls type I error and outperforms state-of-the-art methods with respect to statistical power. Additionally, we find novel associations for multiple A. thaliana phenotypes, and for a study of rare variants in migraine patients.

read more

Wissenschaftler sagen Tulpen-Müllbergen den Kampf an

Wissenschaftler sagen Tulpen-Müllbergen den Kampf an

Zierpflanzen, Stauden oder Schnittblumen sind hierzulande extrem beliebt, vor allem in der Woche vor Muttertag brummt das Geschäft. Dieses Jahr allerdings ist die Nachfrage nach Blumenschmuck oder Sträußen trotz Muttertag eingebrochen, weil aufgrund der Corona-Pandemie viele Veranstaltungen wie Hochzeiten abgesagt wurden. Das Problem, dass die Nachfrage nach gärtnerischen Produkten stark von externen Faktoren wie Witterung, Feiertagen, regionalen Veranstaltungen oder anderen – oftmals noch unbekannten – Einflussfaktoren abhängig ist, besteht für viele Wertschöpfungsketten im Gartenbau.

read more

Two new research projects are funded!

We are pleased to announce that two new research projects will be funded by the Federal Office for Agriculture and Food as well as the Bayerisches Staatsministerium für Ernährung, Landwirtschaft und Forsten.

read more

New Publication in Nucleic Acids Research

New Publication in Nucleic Acids Research

We are pleased to announce the next generation of the online resources AraPheno (https://arapheno.1001genomes.org) and the AraGWAS Catalog (https://aragwas.1001genomes.org) which has just been published in the journal Nucleic Acids Research (https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz925/5603218). AraPheno is a central and manually curated repository for high-quality phenotypes for the model organism Arabidopsis thaliana. As of September 2019 AraPheno contains more than 462 publicly available phenotypes, making it the largest data resource for population-scale phenotypes in A. thaliana, by far. With this release, AraPheno has been extended to support RNA-Seq expression profiles for thousands of samples and genes. 

read more

New Publication in Oxford Database

New Publication in Oxford Database

Dominik Grimm contributed as a member of the international RELISH Consortium to create a large annotated dataset for benchmarking document similarity literature search. The manuscript with the title “Large expert-curated database for benchmarking document similarity detection in biomedical literature search” got published in the journal Database – The Journal of Biological Databases and Curation from Oxford Academic (link).

read more

Kontakt

Professorship Bioinformatics

Petersgasse 18
94315 Straubing

Head

Prof. Dr. Dominik Grimm

Phone: +49 (0) 9421 187-230
Fax: +49 (0) 9421 187-285
E-Mail: dominik.grimm@hswt.de

Team Assistent

Ingrid Meindl

Phone: +49 (0) 9421 187-271
Fax: +49 (0) 9421 187-285
E-Mail: ingrid.meindl@hswt.de